Oral manifestations of Langerhans Cell Histiocytosis (LHC): review of scientific literature and case report

DSM Martínez, UJ Villagrán, RR Ajqui, CK Cervantes


Langerhans cell histiocytosis (LCH) is a dendritic cell disease. It is classified into two variations: localized or disseminated. Frequency per year is  1 in 200,000 children under 15 years of age. Aggressive forms of the disease are mainly found in younger children. This disease presents oral manifestations, which can sometimes be the first expression  of the condition. With relative frequency, jaws can result affected. Radiographic study of the condition shows well circumscribed, osteolytic lesions  imparting a pathognomomic “floating teeth” image.  Patients can be afflicted with  lymphadenopathy,  fever, irritability, anorexia, pallor, middle ear otitis and anemia.

The present article conducts a literature review  and presents  the case of  an 11 month old male infant . This case presents  histiocytosis  oral expressions, incidence, clinical characteristics, diagnosis and treatment.

Palabras clave

Langerhans cell histiocytosis, cervical lymphadenopathy, floating teeth, premature exfoliation

Texto completo:


DOI: http://dx.doi.org/10.22201/fo.1870199xp.2012.16.2-ING.30920


Esp. Daniela Carmona Ruiz


Tel. (55) 5623 22 07

ISSN: 1870-199X