Prevalence of Chronic Diseases in Patients Diagnosed with Intraepithelial Lesion of the Cervix

Abstract

Objective: to identify the association between chronic diseases and intraepithelial lesion of the cervix in women between 25 and 60 years, in a Family Medicine Unit. Methods: cross-sectional analytical study, carried out from June to October 2020, through a simple random probability sampling. 533 women were included in the sample, from 25 to 60 years, with screening for cervical cancer by cervical cytology during 2019. Chronic disease was considered to be present when there was a record of personal pathological background in the clinical history or medical note in the electronic medical record. The cervical cytology result was classified as normal, based on the Bethesda System, when there was no presence of hpv or cellular atypia; low-grade lesion when there was presence of hpv and cervical intraepithelial neoplasia (cin) 1; high-grade lesion with report of cin 2, cin 3 and cancer in situ. Descriptive statistics; bivariate analysis and logistic regression were performed to establish association with or, 95% ci and p-value. Results: according to the cervical cytology report, it was normal in 69.8% (372/533), atypia in 3% (16/533), cin 1 in 17.4% (93/533), cin 2 in 5.6% (30/533), cin 3 in 3.4% (18/533) and cancer in situ in 0.8% (4/533). The chronic conditions associated with intraepithelial lesions were bmi ≥30 with or 1.3 and smoking or 3.3. Conclusion: in this investigation, three out of ten women presented intraepithelial lesion in the cervix. Smoking and obesity were identified as risk factors for squamous intraepithelial lesions of the cervix.