Therapeutic Adherence in Type 2 Diabetes Patients Treated with Metformin and Sitagliptin
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Abstract
Objective: to estimate therapeutic adherence in patients with type 2 diabetes who have initiated combination therapy based on sitagliptin with metformin. Methods: an analytical cross-sectional study where the sample size consisted of 320 patients, obtained using the formula for finite proportions by non-randomized sampling by quotas. During the period from March to September 2022, therapeutic adherence was evaluated in patients who initiated sitagliptin therapy with metformin using the MMAS-8 scale. Descriptive statistics were used to analyze qualitative variables, such as frequencies and percentages, and quantitative variables were measured for central tendency and dispersion. Inferential statistics were analyzed using X2. Results: 55.6% of the patients had average therapeutic adherence. The analysis found no statistically significant association between gender and therapeutic adherence (p= 0.796). Most participants with basic education had medium therapeutic adherence, and there were no significant differences between the levels of schooling (p= 0.89). Comorbidities were present in 80.9% of the participants, with a predominance of medium therapeutic adherence, but no significant association was found (p= 0.620). Conclusion: the therapeutic adherence was only moderate. Improving adherence is a significant challenge for healthcare professionals, and further research should be conducted to optimize the management of chronic diseases.
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