Effect of the induction of moderate hyperprolactinemia on sexual behavior in Wistar male rats.

Article Sidebar

PDF
Published: Jun 8, 2015
DOI: https://doi.org/10.22201/fesi.20070780.2015.7.1.50183

Main Article Content

Luz Irene Pascual-Mathey
Centro de Investigaciones Cerebrales, Universidad Veracruzana, Xalapa, Ver., México
Sara Rodríguez Romero
Pablo Becerra Lara
Jorge Manzo
Maria Elena Hernández

Abstract

At physiological high levels, Prolactin (PRL) is related with many functions, including lactation, reproduction and sexual behavior. Abnormal high levels, referred to as hyperprolactinemia (HP), are associated with sexual disorders like hypogonadism, erectile dysfunction and infertility. Male rats with HP display less mounts and intromissions, as well as higher ejaculation latencies, however, little is known about the effect of modest HP. To learn more about this topic, the study aims to analyze the effect of a moderate HP (40 ng/ml), induced by pituitary transplantation and ovine PRL administration (100µg/d), on sexual behavior of sexually experienced male rats. Sixty-four sexually experienced male rats were randomly assigned to 4 groups: 1) Ctrl; 2) oPRL; 3) Graft and; 4) Sham. During a time of 15 days, rats were subjected to a sexual behavior test every three days. The last day, sexual behavior was tested with the SBR Software. Results showed that pituitary graft produced and increase in the number of mounts, and longer intromission-ejaculation latencies compared with controls. Also, we found that hit rate was reduced. Interestingly, these parameters are related with the anticipatory/consummatory phases of the sexual behavior, suggesting a role of PRL in males with not chronic HP.

Article Details

How to Cite
Pascual-Mathey, L. I., Rodríguez Romero, S., Becerra Lara, P., Manzo, J., & Hernández, M. E. (2015). Effect of the induction of moderate hyperprolactinemia on sexual behavior in Wistar male rats. Journal of Behavior, Health & Social Issues, 7(1), 9–17. https://doi.org/10.22201/fesi.20070780.2015.7.1.50183

Esta revista es de acceso libre inmediato a su contenido, bajo el principio de hacer disponible al público gratuitamente las investigaciones publicadas.

Los autores que publiquen en Journal of Behavior, Health and Social Issues (JBHSI) aceptan las siguientes condiciones:

  1. De acuerdo con la legislación de derechos de autor, en Journal of Behavior, Health and Social Issues (JBHSI) reconoce y respeta el derecho moral de los autores, así como la titularidad del derecho patrimonial, el cual será transferido —de forma no exclusiva— a la revista para su difusión en acceso abierto.
  2. La revista Journal of Behavior, Health and Social Issues (JBHSI) no realiza cargos a los autores por enviar y procesar artículos para su publicación.
  3. Todos los textos publicados por en Journal of Behavior, Health and Social Issues (JBHSI)

—sin excepción— se distribuyen amparados bajo la Licencia Creative Commons Atribución- NoComercial 4.0 Internacional, que permite a terceros utilizar lo publicado siempre que mencionen la autoría del trabajo y a la primera publicación en esta revista.

  1. Los autores pueden realizar otros acuerdos contractuales independientes y adicionales para la distribución no exclusiva de la versión del artículo publicado en Journal of Behavior, Health and Social Issues (JBHSI), por ejemplo incluirlo en un repositorio institucional o darlo a conocer en otros medios en papel o electrónicos, siempre que indique clara y explícitamente que el trabajo se publicó por primera vez en el Journal of Behavior, Health and Social Issues (JBHSI).
  2. Para todo lo anterior, los autores deben remitir el formato de carta de transmisión de derechos patrimoniales de la primera publicación debidamente requisitado y firmado, al momento de ser aceptado para su publicación el manuscrito en cuestión.

 

 

This is an open-access journal in terms of its content, under the premise of making published research available to the public for free.

The authors who publish on the Journal of Behavior, Health and Social Issues (JBHSI) accept the following terms:

  1. In accordance to the copyright law, the Journal of Behavior, Health and Social Issues (JBHSI) recognizes and respects the moral law of the authors, as well as the ownership right, which will be transferred –in a non-exclusive manner- to the journal for its open access diffusion.
  2. The Journal of Behavior, Health and Social Issues (JBHSI) does not charge the authors for sending and processing the papers for their publication.
  3. Every text published by the Journal of Behavior, Health and Social Issues (JBHSI) –with no exception- is distributed under protection of the Creative Commons Attribution 4.0 International license, which allows third parties to utilize what was published as long as they mention the authorship of the paper and the first publication in this journal.
  4. The authors can hold other contractual agreements, independent and additional to the non-exclusive distribution of the published version of the article in the Journal of Behavior, Health and Social Issues (JBHSI), such as including it in an institutional repository or promoting it through channels different from paper or electronic publications, as long as it indicates clearly and explicitly that the paper was first published in the Journal of Behavior, Health and Social Issues (JBHSI).
  5. For all the previous matters, the authors must refer the format of the letter of transference of patrimonial rights of the first publication, properly required and signed, at the moment of being approved for publication in the manuscript at issue.