Aggressive central giant cell granuloma of the maxilla: treatment with triamcinolone infiltration and curettage

Abstract

Introduction: central giant cell granuloma (CGCG) is a locally aggressive, benign osteolytic lesion of the jaws characterized by the presence of osteoclast-like giant cells in a vascular stroma. About 30% of cases present aggressively, characterized by rapid growth, greater than 5 cm, pain, cortical perforation and invasion of peripheral tissue and root resorption. They are aggressive and non-aggressive. Objective: to present the case of an aggressive central giant cell granuloma treated with several therapeutic resources. Case presentation: a 35-year-old female patient with an aggressive central giant cell granuloma on the right side of the maxilla, treated with triamcinolone infiltration following the Jacoway protocol and subsequent enucleation and surgical curettage. Results: the total size of the lesion was reduced by approximately 30%, followed by enucleation and curettage, with a year control; currently no recurrence. The use of auxiliary therapies to surgery, such as intralesional corticosteroid infiltration, is a useful treatment in the management of central giant cell granuloma, allowing surgery to be less radical and traumatic in most cases, therefore, and a decrease in morbidity in the patient.